Sequential Involvement of the Nervous System in Subacute Combined Degeneration

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Sequential Involvement of the Nervous System in Subacute Combined Degeneration

PURPOSE Subacute combined degeneration (SCD) involves progressive degeneration of the spinal cord, optic nerve, and peripheral nerves. Vitamin B12 (VB12) is a co-factor in myelin synthesis. Because each cell that constitutes the myelin component in the central nervous system and peripheral nervous system is different, it is improbable that these cells undergo simultaneous degeneration. However,...

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Subacute combined degeneration : report of two cases

Subacute combined degeneration ( SCD) due to vitamin B12 deficiency is common in North of Europe but sometimes it is seen in Iran. It can develop before the symptoms of anemia is obvious, with myelin injury and then axon and even neuron destruction in spinal cord, brain, optic and peripheral nerves. In this study two cases are reported; in the first patient, this disease in manifested by vitami...

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SUBACUTE combined degeneration of the spinal cord.

This paper describes the clinical history of an adult male who was found to be suffering from subacute combined degeneration of the spinal cord. It is believed that this is the first report of this condition in Papua New Guinea.

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Magnetic resonance findings in subacute combined degeneration.

2. Hathout L, El-Saden S. Nitrous oxide-induced B12 deficiency myelopathy: perspectives on the clinical biochemistry of vitamin B12. J Neurol Sci. 2011;301(1-2):1-8. https://doi.org/10.1016/j.jns.2010.10.033 3. Gupta PK, Gupta RK, Garg RK, Rai Y, Roy B, Pandey CM et al. DTI correlates of cognition in conventional MRI of normal-appearing brain in patients with clinical features of subacute combi...

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ژورنال

عنوان ژورنال: Yonsei Medical Journal

سال: 2012

ISSN: 0513-5796,1976-2437

DOI: 10.3349/ymj.2012.53.2.276